UR Medicine Is Building a 172,000-Square-Foot Outpatient Clinic at the Former Marketplace Mall

The Marketplace Mall closed in December 2025, and if you drove past it this winter, it looked like exactly what it was — 43 years of regional retail history sitting empty. What's replacing it is something the region will use a lot differently. The University of Rochester is seeking final site plan approval to build a 172,000-square-foot UR Medicine outpatient clinic in Henrietta, one step from starting construction on a facility that brings specialist care closer to Pittsford than it has ever been.

Final Approval Pending for the New UR Medicine Outpatient Clinic

Final Approval Pending for the New UR Medicine Outpatient Clinic

The Henrietta Planning Board took up UR's application on October 15, 2026 — the last formal hurdle before construction can begin at 3400 West Henrietta Road, in the northwest corner of the former mall. This isn't a renovation. The existing structure is being demolished and the clinic built in the same footprint from the ground up. Town Supervisor Stephen Schultz explained that medical facilities require air-handling systems far heavier than what the original retail roof and foundations can support, which rules out any retrofit. The new building connects directly to the Saunders Center for Orthopaedics and Physical Performance, which opened in February 2023 and sits immediately to the south. This is a campus expansion, not a standalone outpost.

Pediatric Specialists, Adult Care, and the Golisano IDD Institute Under One Roof

Pediatric Specialists, Adult Care, and the Golisano IDD Institute Under One Roof

The clinic has two distinct functions. One portion houses pediatric and adult medical specialists providing diagnostic, treatment, and complementary care. For families in Pittsford, that means specialist appointments that currently require a trip to the Strong Memorial campus will be available on the west side of Monroe County instead.

The second portion accommodates the Golisano Intellectual and Developmental Disabilities Institute, sharing a wall with the planned Mary Cariola Center immediately to the east. The Mary Cariola Center has served children and adults with developmental disabilities for more than 75 years. Moving to this campus means the people Mary Cariola serves can access clinical IDD care and specialized education in the same building, on the same visit. Tom Golisano committed $75 million toward the combined project, and New York State added $4 million.

"New York is proud to support the Mary Cariola Center as it reimagines this former retail space into a hub of opportunity, care and inclusion."

— Governor Kathy Hochul

How the Old Marketplace Mall Became a Regional Medical Campus

How the Old Marketplace Mall Became a Regional Medical Campus

The Saunders Center was the first move in what has become a deliberate campus strategy. UR broke ground in June 2021 on a $227 million, 330,000-square-foot facility — the largest offsite building project in the university's history — and projected 7,000 surgeries in 2024. That volume, from a building that didn't exist five years ago, is the reason UR is expanding into the rest of the mall footprint.

The mall's formal closure in December 2025 cleared the path for the rest of the site. Henrietta's Town Board approved special use permits on May 29, 2026. The October Planning Board hearing on the outpatient clinic is the final step in the formal approval chain.

What's taking shape at 3400 West Henrietta Road is a purpose-built medical campus: specialist care, orthopaedics, IDD services, and specialized education for people who previously had no single destination for all of it. The site is in Henrietta, on a road most Pittsford residents know.